About   Help   FAQ
Symbol
Name
ID 		Esr2
estrogen receptor 2 (beta)
MGI:109392
Phenotype annotations related to reproductive system
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations
Human Phenotypes
Eclampsia
Maternal hypertension
Preeclampsia
Clitoral hypertrophy
Hypoplastic labia majora
Hypospadias
Penoscrotal hypospadias
Perineal hypospadias
Prostate cancer
Polycystic ovaries
Uterine leiomyosarcoma
Primary amenorrhea
Female sexual dysfunction
Male sexual dysfunction
Disease(s) Associated with ESR2
colorectal cancer
hypospadias
ovarian dysgenesis 8
Parkinson's disease
pre-eclampsia
prostate cancer

Mouse Phenotypes
reproductive system phenotype
abnormal germ cell morphology
abnormal mammary gland growth during pregnancy
prostate gland epithelial hyperplasia
absent corpus luteum
decreased corpora lutea number
abnormal cumulus oophorus morphology
absent mature ovarian follicles
increased secondary ovarian follicle number
increased atretic ovarian follicle number
impaired ovarian folliculogenesis
abnormal tertiary ovarian follicle morphology
abnormal superovulation
decreased superovulation rate
failure of superovulation
anovulation
decreased ovulation rate
abnormal estrous cycle
female infertility
reduced female fertility
decreased litter size
male infertility
Availability Mouse Genotype
Esr2tm1.1Gust/Esr2tm1.1Gust *
Esr2tm1.1Ksk/Esr2tm1.1Ksk
Esr2tm1.2Pcn/Esr2tm1.2Pcn *
Esr2tm1Mma/Esr2tm1Mma *
Esr2tm1Unc/Esr2tm1Unc *
Esr2tm1Mma/Esr2+ *
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory